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Updated Dec 19, 2022 116 Questions 8 Pages
Page 7 of 8
Question 91 Written Answer
CORRECT TEXT
Match terms with fragments resulting from papain digestion of an IgG molecule:



A = Fab fragment OR Fc fragment
B = Fab fragment OR Fc fragment

Answer: A, B
Question 92 Selectable Answer
Monoclonal antibodies are monospecific antibodies that are the same because they are made by one type of immune cell which are all clones of a unique parent cell, also called a hybrid cell line, which usually arise from a hybridoma. The fusion of a specific antibody-producing lymphocyte with a myeloma cell will multiply to become a source of pure monoclonal antibody. This is often used in the manufacturing process for monoclonal antibody reagents.
Monoclonal antibodies are usually manufactured in vitro by using:

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Question 93 Selectable Answer
A laboratory scientist is working the night shift at a local hospital when the power goes out.
What is the course of action to continue to provide laboratory results?

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Question 94 Selectable Answer
Serological diagnosis of active or recent infection generally requires the demonstration of IgM antibody, or the demonstration of a fourfold rise in the titer of specific IgG antibody.
Which of the following would be considered most significant as it relates to serological testing?

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Question 95 Selectable Answer
The structures involved in the production of semen include the prostate, the seminal vesicles, and the bulbourethral gland, along with the testes and epididymis.
Semen is produced as a combination of secretions from the different regions of the male reproductive tract. Each fraction differs in chemical composition and function.
Spermatozoa are produced in the testes. They mature in the epididymis. The testes also produce testosterone and inhibin.
Fluid from the seminal vesicles accounts for approximately 70% of semen volume. The seminal vesicles are the source of fructose in semen. Fructose is used by the spermatozoa as an energy source.
The prostate gland supplies about 20% of the volume of semen. Its fluids include acid phosphatase and proteolytic enzymes that lead to coagulation and subsequent liquefaction of semen. The prostate also contains most of the IgA found in semen.
The bulbourethral gland produces mucoproteins that make up about 5% of the volume of semen.
The pituitary gland is not directly involved in the production of semen; instead hormones are released which stimulate the production of sperm. The urethra is not involved in the production of semen.
Which of the following are directly involved in the production of semen?

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Question 96 Selectable Answer
Plasma concentrations of creatinine are used to assess renal function. Creatinine clearance is based on the serum creatinine level and is used to measure glomerular filtration rate, or GFR.
An increased serum level of which of the following analytes is MOST commonly associated with decreased glomerular filtration?

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Question 97 Written Answer
The area of the federal government that ensures that the laboratory is stocked with gloves for their employees when performing tests on patient blood sample is:
A. CDC.
B. OSHA
C. HIPAA.
D. FDA.

Answer: B
Question 98 Selectable Answer
One of the key characteristics to the identification of Nocardia asteroides is its inability to hydrolyze casein, tyrosine or xanthine, as shown in this photograph. Nitrates are reduced to nitrites. Both Nocardia brasiliensis and Actinomadura madurae hydrolyze both casein and tyrosine; Streptomyces griseus hydrolyzes all three of the substrates.
Illustrated in this photograph is an agar quadrant plate containing casein (A), tyrosine (B), nitrate (C) and xanthine (D). None of the substrates have been hydrolyzed and nitrate has been reduced. The most likely identification is:


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Question 99 Selectable Answer
The morphologic characteristic(s) associated with the Chediak-Higashi syndrome is (are):

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Question 100 Selectable Answer
Porphobilinogen

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Question 101 Selectable Answer
If all newborns were tested, many positive DATs due to ABO incompatibility would be detected that are of no clinical significance.
Although many laboratories test infants born to group O Rh positive females due to the higher risk of ABO HDFN when the mother is group O, testing such infants is optional provided there is appropriate monitoring and follow-up for hyperbilirubinemia.
Blood Bank
Not performing direct antiglobulin tests (DATs) on newborns born to group O Rh positive mothers is acceptable good practice, providing there is appropriate surveillance and follow-up to detect hyperbilirubinemia.

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Question 102 Selectable Answer
Provide the equivalent measurement for one gallon.
Question options:

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Question 103 Selectable Answer
The tube of choice for trace metal analysis is:

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Question 104 Selectable Answer
Enrichment

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Question 105 Selectable Answer
Triglyceride blood concentrations change significantly when you eat, as opposed to relatively stable levels of cholesterol, HDL, or LDL circulating in the blood. Whenever you eat a meal that contains fat, your triglyceride levels rise, which is why it is important to have a patient fast before the sample is collected.
Which of the following lipid results would be expected to be FALSELY elevated on a serum specimen from a non-fasting patient?

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