Question 31
Selectable Answer
Which of the following is NOT part of the stand or framework of the microscope?
Answer:
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Question 32
Selectable Answer
If Kappa or Lambda is predominant and CD5 is co-expressed with CD19 (CD19/CD5 dual positive lymphocyte population), and CD23 is expressed, chronic lymphocytic leukemia is a probable diagnosis. CD19 is normally found on normal B cell populations and CD5 is normally found on mature T cell populations. However, CD5 is present on B cells in B-chronic lymphocytic leukemia or Mantle Cell Lymphoma, both abnormal B cell malignant processes.
CD23 expression is not consistent with Mantel cells as shown on the decision tree on the right.
A monoclonal B-cell population (Kappa or Lambda predominant) with expression of CD19, CD20, CD23, and co-expression of CD5 is consistent with which of the following?
CD23 expression is not consistent with Mantel cells as shown on the decision tree on the right.
A monoclonal B-cell population (Kappa or Lambda predominant) with expression of CD19, CD20, CD23, and co-expression of CD5 is consistent with which of the following?
Answer:
Question 33
Selectable Answer
As maturation continues in the granulocytic series the nucleus of the metamyelocyte becomes kidney or bean shaped.
Identify the cell in this illustration indicated by the arrow:
Identify the cell in this illustration indicated by the arrow:
Answer:
Question 34
Selectable Answer
Hematology
What is Coombs sera comprised of:
What is Coombs sera comprised of:
Answer:
Question 35
Selectable Answer
Which of these advancements in the clinical laboratory has led to concerns about patient privacy
Answer:
Question 36
Selectable Answer
This type of laboratory professional is responsible for the technical aspects of managing
the operation of the laboratory and is most likely an MLS with additional education in administration:
the operation of the laboratory and is most likely an MLS with additional education in administration:
Answer:
Question 37
Selectable Answer
Once substance H is developed, the addition of the sugar N-acetylgalactosamine to the terminal position of the chain gives the molecule "A" antigenic activity.
Which specific terminal sugar causes a red cell to have A antigenic activity?
Which specific terminal sugar causes a red cell to have A antigenic activity?
Answer:
Question 38
Selectable Answer
This patient is most likely suffering from an immediate-acting coagulation inhibitor; most commonly, lupus anticoagulant. Notice that the addition of normal pooled plasma does not correct upon initial or incubated mix, which means that the inhibitor is not time or temperature-dependent.
Factor VIII is not the correct answer as a factor deficiency would have corrected upon the addition of normal pooled plasma. Factor VII is not the correct answer, as the aPTT assay does not account for factor VII activity or concentration.
The laboratorian completed the mixing study ordered for John Doe. The results are as follows:
Initial aPTT result: 167 seconds
Initial 1:1 Mix with Normal Pooled Plasma: 158 seconds
Incubated 1:1 Mix with Normal Pooled Plasma: 150 seconds
Which of the choices below would most likely explain the results for this patient?
Factor VIII is not the correct answer as a factor deficiency would have corrected upon the addition of normal pooled plasma. Factor VII is not the correct answer, as the aPTT assay does not account for factor VII activity or concentration.
The laboratorian completed the mixing study ordered for John Doe. The results are as follows:
Initial aPTT result: 167 seconds
Initial 1:1 Mix with Normal Pooled Plasma: 158 seconds
Incubated 1:1 Mix with Normal Pooled Plasma: 150 seconds
Which of the choices below would most likely explain the results for this patient?
Answer:
Question 39
Selectable Answer
The MCV is indicative of microcytosis with MCV=<80fL. The RDW is within normal limits and indicative of a homogenous cell population.
If the MCV was >100 fL, this would be indicative of macrocytosis. An RDW that was outside of normal limits would be indicative of a heterogenous cell population.
An 18 year old female has a CBC as part of a routine physical exam. The following results were obtained and the physician determines she is anemic. After reviewing her CBC results shown below, which of the following would be an appropriate description of the anemia?
White blood cells (WBC): 5.6 x 10^9/L (RR:4.0-10.0 x 10^9/L)
Red blood cells (RBC): 3.7 x 10^12/L (RR: 4.2-5.9 x 10^12/L)
Hemoglobin: 9.9 g/dL (RR:12-16 g/dL)
Hematocrit: 28% (RR: 37-48%)
MCV: 75 fL (80-100 fL)
RDW-CV: 14% (RR: 11.0-15.0%)
If the MCV was >100 fL, this would be indicative of macrocytosis. An RDW that was outside of normal limits would be indicative of a heterogenous cell population.
An 18 year old female has a CBC as part of a routine physical exam. The following results were obtained and the physician determines she is anemic. After reviewing her CBC results shown below, which of the following would be an appropriate description of the anemia?
White blood cells (WBC): 5.6 x 10^9/L (RR:4.0-10.0 x 10^9/L)
Red blood cells (RBC): 3.7 x 10^12/L (RR: 4.2-5.9 x 10^12/L)
Hemoglobin: 9.9 g/dL (RR:12-16 g/dL)
Hematocrit: 28% (RR: 37-48%)
MCV: 75 fL (80-100 fL)
RDW-CV: 14% (RR: 11.0-15.0%)
Answer:
Question 40
Selectable Answer
Alcaligenes faecalis
Answer:
Question 41
Selectable Answer
The term that is used to describe the color in these tubes of CSF is "xanthochromia." Xanthochromia is an abnormal color, usually yellow, orange, or pink, in the supernatant of the CSF sample. It may indicate that a subarachnoid hemorrhage (SAH) has occurred.
Jaundice and icterus both describe a yellowing of the skin, mucous membranes, and eyes.
Blood plasma/serum that is deep yellow is also described as icteric.
What term is used to describe the color in these tubes of cerebrospinal fluid (CSF)?
Jaundice and icterus both describe a yellowing of the skin, mucous membranes, and eyes.
Blood plasma/serum that is deep yellow is also described as icteric.
What term is used to describe the color in these tubes of cerebrospinal fluid (CSF)?
Answer:
Question 42
Selectable Answer
Neutrophils reside in the peripheral circulation for only 7-8 hours ( approx. 7.5 hours) before entering the tissues and body cavities. This process is called diapedesis.
Hematology
How long are healthy neutrophils expected to reside in the peripheral blood of an adult?
Hematology
How long are healthy neutrophils expected to reside in the peripheral blood of an adult?
Answer:
Question 43
Selectable Answer
Neutrophils are typically increased in urinary bacterial infections.
What type of white blood cell is seen MOST frequently in urine sediment with infections of the urinary system?
What type of white blood cell is seen MOST frequently in urine sediment with infections of the urinary system?
Answer:
Question 44
Selectable Answer
IgE levels are often increased in patients with allergic disease. IgE binds to the membranes of mast cells and basophils, and if specific antigen is present to react with the IgE molecule, degranulation of these cells occurs, releasing histamines, and other substances into the blood or tissues.
Which of the following immunoglobulin classes is chiefly responsible for the degranulation of mast cells and basophils:
Which of the following immunoglobulin classes is chiefly responsible for the degranulation of mast cells and basophils:
Answer:
Question 45
Selectable Answer
The combination of complement C4, C2 and C3 that binds to the antigen-antibody complex in the initial reaction step in the classical pathway of complement activation is called the activation unit.
Which of the following is the "activation unit" in the classical complement pathway?
Which of the following is the "activation unit" in the classical complement pathway?
Answer:
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